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Abstract Acute pancreatitis (AP), a life-threatening gastrointestinal emergency, is characterized by acute onset, rapid clinical deterioration, and high mortality rates, imposing profound long-term health burdens and socioeconomic costs on patients and healthcare systems

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Key metabolic pathways such as citrate cycle, pentose phosphate pathway, glycolysis, and L-phenylalanine biosynthesis play essential roles in supporting drought tolerance [9]

145,146,286 Cells lacking arginine-succinate synthetase 1 (ASS1) are arginine-dependent

CJC-1295 is a modified GHRH analogue based on the same GRF 1-29 backbone as sermorelin, but with four amino acid substitutions (Ala2D-Ala, Asn8Gln, Ala15Ala(NMe), Leu27Leu(NMe)) that improve resistance to DPP-IV degradation