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L.BertschU.SalwenderH.et al (2012)

During the later stages of M1 polarization, driven by lactate produced during early inflammation, Kla appears to replace Kac, activating genes involved in inflammation resolution and homeostatic repair (6)

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The formation of the complex is further stabilized by several interactions between hTrx1 residues 58 hTrx1 to 74 hTrx1 and the helical hTrxR1 residues Glu103 hTrxR1 to Glu122 hTrxR1 (Fig