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doi: 10.1016/j.cell.2023.05.003 89 ChuCCPaulWE

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These changes were closely linked to reduced colonic inflammation and restored mucosal structure, indicating that the antioxidant action of triptolide contributed significantly to its protective effects in stress-related GI dysfunction

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BMAL1/ARNTL deficiency triggers the production of pro-inflammatory cytokines [373], which could pave the way for further consideration of BMAL1/ARNTL in the extended pathogenesis of COVID-19