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The lyophilized format is preferred for research because it eliminates solution-phase degradation during storage and allows precise gravimetric preparation of research concentrations at the point of use

N-Aryl-N-(chroman-4-yl) ureas and thioureas display in vitro anticancer activity and selectivity on apoptosis-resistant glioblastoma cells: screening, synthesis of simplified derivatives, and structure-activity relationship analysis

Cancers (Basel) 12 (5), 11191125

Methionine oxidation is especially problematic

Clin Exp Hypertens A 12:13511360 Jackson AA, Dunn RL, Marchand MC, Langley-Evans SC (2002) Increased systolic blood pressure in rats induced by a maternal low-protein diet is reversed by dietary supplementation with glycine