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References ACS Chemical Biology (2023) Synthetic ERR// Agonist Induces an ERR-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity Journal of Pharmacology and Experimental Therapeutics (2024) A Synthetic ERR Agonist Alleviates Metabolic Syndrome Circulation (2024) Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function American Journal of Pathology (2023) Estrogen-Related Receptor Agonism Reverses Mitochondrial Dysfunction and Inflammation in the Aging Kidney

Clinical evidence: A study published in the Journal of Clinical Endocrinology and Metabolism demonstrated that CJC-1295 increased mean GH concentrations by 2 to 10-fold and IGF-1 levels by 1.5 to 3-fold (Teichman et al., 2006)

Metabolism 100, 31123117

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(B) For CY 2019 through CY 2026, the hospital inpatient market basket percentage increase determined under paragraph (a)(2)(iii) of this section, after application of any reduction under paragraph (a)(2)(v) of this section, is reduced by the productivity adjustment described in section 1886(b)(3)(B)(xi)(II) of the Act