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[30] The C-terminal catalytic domain The C-terminal catalytic domain, which contains the active site, consists of 250 amino acid residues arranged into a hollow, cage-like structure containing channels large enough to allow substrates and products to diffuse in and out

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Obstructive sleep apnea (OSA) and pulmonary arterial hypertension (PAH) David Flenley coined the term Overlap Syndrome (OS) when he described Obstructive Sleep Apnea (OSA) in patients with COPD and showed that they had a higher risk of mortality and ECOPD 119

Glutathione is a powerful defence nutrient that is extremely important for cell protection and is highly active in the liver, heart, lungs and brain

LCMS data analysis and metabolic flux analysis were performed using published software, as indicated in Methods