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579 Clasmatodendrosis of astrocytes was observed in the majority of post-mortem samples from FTD patients

These signals drive serine phosphorylation of the insulin receptor substrate IRS1, thereby blocking insulin signal transduction and contributing to insulin resistance (McLaughlin et al., 2017)

Sex differences in the expression of hepatic drug metabolizing enzymes (DME) are documented for genes/enzymes of the primary metabolism (CYP450s), secondary metabolism (i.e