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LKB1 inhibits CPS1 expression through AMPK, whereas CPS I expression is elevated in KRAS/LKB1 -mutant NSCLC cells (Shackelford and Shaw, 2009)

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This attenuation of the wound-induced jasmonate burst was reflected in lower wound- and jasmonate-responsive gene expression in plants grown at eCO 2 compared with aCO 2 , a distinction abolished in the cyp203 mutants ( Figure 4 )

Disclosures: Moad Ekreer: Nothing to Disclose, Mohammad Al Hayek: Nothing to Disclose, Mohamed Salah Alhateem: Nothing to Disclose, Abdallah Khashan: Nothing to Disclose, Raja Abeedah: Nothing to Disclose, Omar Aghneewah: Nothing to Disclose, Fatimah Alzahra Abduljawad: Nothing to Disclose, Muhammed Elhadi: Nothing to Disclose 1641 GENETIC AND PHARMACOLOGICAL TARGETING OF HEPATIC OXALATE OVERPRODUCTION AMELIORATES METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS Oren Rom 1 Sandeep Das 2 Alexandra Finney 2 Sumit Anand 1 Sumati Rohilla 2 Yuhao Liu 3 Nilesh Pandey 2 Alia Ghrayeb 2 Dhananjay Kumar 2 Kelley Nunez 4 Zhipeng Liu 5 Fabio Arias 6 Ying Zhao 3 Brenna Pearson-Gallion 2 Peyton McKinney 2 Koral Richard 2 Jose Antonio Gomez-Vidal 6 Chowdhury S

For instance, a minimum intracellular selenium status (in terms of the concentration of hydrogen selenide) is required for the translation of all seleno-GPxs