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This inhibition also causes AKT dephosphorylation and dysfunction

Through the production of both singlet oxygen and nitric oxide, this method improved tumor cell killing [185]

The uniform placement of Fe and Mn atoms in the structure indicates the generation of Fe and Mn double sites in the three-dimensional matrix

Collectively, cytochrome c release and caspase activation driven by iron-induced ROS are the common routes for the activation of intrinsic apoptosis and pyroptosis, while the suppression of short Fas by iron is a common route for the activation of extrinsic apoptosis and necroptosis