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This has been shown to be concentration-dependent, as well as consistent across species and myocardial preparations ( Extracellular Ca 2+ influx and L-type Ca 2+ channels The arrhythmic and positive inotropic manifestations of myocardial LCAC superfusion have been reported to increase in amplitude and frequency proportionally with increases in extracellular Ca 2+ concentration ( 2+ superfusion medium ( 2+ acutely evoked by LCAC superfusion was significantly blunted with EGTA chelation of extracellular Ca 2+ ( 2+

No significant differences in CMAP were detected between different concentrations of PNM (PNM-10, 0.131 0.031 mV

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Di Patria L, Annibalini G, Morrone A, Ferri L, Saltarelli R, Galluzzi L, Diotallevi A, Bocconcelli M, Donati MA, Barone R, Guerrini R, Jaeken J, Stocchi V, Barbieri E (2022) Defective IGF-1 prohormone N-glycosylation and reduced IGF-1 receptor signaling activation in congenital disorders of glycosylation