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An FDA-approved drug comes with a defined indication, a validated dosing protocol, a safety surveillance system, and manufacturer accountability

A common point of confusion is that many vials labeled "TB-500" actually contain full-length synthetic T4, so the precise molecule matters more than the trade name

Users, even enthusiastic ones, have reported side effects including hair loss, blurred vision, rashes, and dizziness

It is summarized here for completeness because subsequent work, including Sun et al

14: Bajramagic S, Sever M, Rasic F, Staresinic M, Skrtic A, Beketic Oreskovic L, Oreskovic I, Strbe S, Loga Zec S, Hrabar J, Coric L, Prenc M, Blagaic V, Brcic K, Boban Blagaic A, Seiwerth S, Sikiric P