mega l carnitine L-Carnitina 700MG 120CAPS. (Quamtrax) Olimp Sport Nutrition L-carnitine 1500

Caffeine prevented lipid peroxidation, as evidenced by increased MDA levels [33, 34, 42], increased antioxidant factors such as SOD and glutathione peroxidase (GSH) [34, 38, 42], reduced acetylcholinesterase activity [37], increased BDNF levels [33, 40] and neurogenesis by reducing p-MEK/MEK, p-ERK1/2/ERK 1/2 e p-NFkB/GPADH ratios [39, 40], neuroprotection measured by KA/3-HK and KA/KYN ratios [32] and restore gut microbiota balance [38]

Tabas and Bornfeldt, 2016

doi: 10.3390/biomedicines10112699 53 ZhouYLongQWuHLiWQiJWuYet al

These approaches are aimed to reverse pathogenic plasticity or promote corrective plasticity (rehabilitation) in the brain

The nutrients that can be considered to supplement the diet to prevent and/or ameliorate migraine are riboflavin, thiamine, magnesium ions, niacin, carnitine, coenzyme Q10, melatonin, lipoic acid, pyridoxine, folate, and cobalamin