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SKU: 11491525571
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Role of Hyperphosphatemia In CKD stages G4-G5 hyperphosphatemia becomes an increasingly frequent feature (21), due to phosphate retention caused by the progressive loss of functioning nephrons and the increasing difficulty in augmenting glomerular phosphate ultrafiltration and to further reduce its tubular reabsorption when it is already maximally inhibited by high serum FGF23 and PTH levels

Isopentenyl pyrophosphate is a precursor of squalene and coenzyme Q10 (CoQ10) and a limiting substrate for enzymatic prenylation of Sec-tRNA (Moosmann and Behl, 2004