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For instance, the amino acid leucine activates the mTOR pathway, which plays a pivotal role in muscle cell growth and response to oxidative stress [50]

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The evolutions in the field of drug discovery open the way to a new generation of senolytic therapies, such as immunological approaches (CAR-T cells, Antibody-Drug Conjugated or vaccines), which require preliminary steps of research to identify markers specifically expressed on senescent cells, demonstrating promising specific effects

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