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Secondary C

The equations for calculating DL (drug loading) and EE (encapsulation efficiency) were as follows: 2.4.4 Nanoparticle stability The stability of GO@GSH and GO@GSH-FA nanoparticles was rigorously assessed in various media, including phosphate-buffered saline (PBS, pH 7.4) with and without reactive oxygen species (ROS)

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The accumulation of ROS is particularly detrimental in cardiac tissues, where it can disrupt calcium homeostasis, contributing to cardiac dysfunction and arrhythmias (79)