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10.1016/j.molbiopara.2016.12.001 Mol

Chen B, Yu H-L, Liu S-L, Liu C-C, Liang L-H, Li X-H, et al

These findings demonstrate that sulforaphane robustly activates NRF2 in the cerebellum and peripheral tissues, protecting them from oxidative stress and leading to a reduction in autism-like behaviors (Nadeem et al., 2019)

Mitochondria are cholesterol-poor organelles compared to plasma membrane, and this regulated transport of cholesterol in mitochondria plays physiological role in the synthesis of bile acids in liver and steroidogenic hormones in other tissues

Those are fundamentally different problems with fundamentally different solutions