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[Abstract] J Drug Deliv Sci Technol

As an important transcription factor, Nrf2 can not only regulate SLC7A11 transcription, but also up-regulate the expression of GSS and GCLC, which are key rate-limiting enzymes for GSH synthesis (Sun et al., 2016a

These differentially expressed metabolites could be enriched in pathways such as degradation of aromatic compounds, biosynthesis of unsaturated fatty acids, pyrimidine metabolism, bile secretion, and glycerophospholipid metabolism, as detailed in Figure 3D

Epigallocatechin gallate for management of heavy metal-induced oxidative stress: Mechanisms of action, efficacy, and concerns

Total AQ and SRS-2 scores were significantly higher in the ASD group