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J Clin Endocrinol Metab 83:16541661 Ding H, Gao XL, Hirschberg R, Vadgama JV, Kopple JD (1996) Impaired actions of insulin-like growth factor 1 on protein synthesis and degradation in skeletal muscle of rats with chronic renal failure

Nieuwenhuys R, Voogd J, van Huijzen C

Galvin, R

438 Notably, two cytokines involved in the mt-ISR, FGF-21 and GDF-15, have shown exceptional diagnostic value for mitochondrial myopathy and tRNA gene mutation-related mitochondrial diseases, and they may also serve as biomarkers for monitoring therapeutic efficacy