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Remarkably, immunofluorescence labeling of neurons (-III-tubulin), astrocytes (GFAP), and oligodendroglia (combining PDGFR and CNP) showed that all 11 selected compounds increased by ~ 1.5-fold the number of oligodendroglial cells compared to vehicle (DMSO or PBS, Methods), as illustrated for Sm11 (Fig

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Many patients improve gradually over months, but older patients or those with severe long-lasting pain may require a structured multimodal plan for sustained pain control

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This helps with healing and keeps muscle mass during weight loss