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Curcumin improves MMC-based chemotherapy by simultaneously sensitising cancer cells to MMC and reducing MMC-associated side-effects

We show here that the Cys-34 crevice substantially reduces the rate of serum stabilising maleimide hydrolysis in these conjugates, necessitating reagent optimisation

4 x 10 4 cells were seeded for the DMSO condition and 8 x 10 4 cells were seeded for the palbociclib condition

32 This versatile seed has also held a prominent place in traditional remedies across Arabian countries, Far East Asia, Europe, and Africa, earning it the nickname The herb from heaven by early herbal specialists

10.1021/acschembio.5b00245 18 DollS.FreitasF