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Tissue Cell 91:102624

Notably, under hypoxic or electron transportlimited conditions, SDH can reverse its activity to reduce fumarate to succinate using electrons from the CoQ 10 pool, a metabolic rerouting, allowing cells to maintain redox balance when oxygen is scarce 77

Quickly disperses medicine Intramuscular injections quickly disperse medications into the bloodstream so that the body can rapidly disperse it where it is needed

Importantly, many of the pathways susceptible to redox modulation are actively involved in the pathogenesis of ALD, including the NRF2 and AMPK pathways

It alleviates hepatic injury by activating the Nrf2/HO-1 antioxidant pathway and suppressing NF-Bmediated inflammation, highlighting its potential as a therapeutic applicant for ALD (94)