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He originally won that season's Brownlow Medal as the league's best and fairest player, but was later ruled ineligible in 2016 as a result of the suspension and subsequently handed back the medal

The exact mechanism involved in the increase of the sensibility to the oxidative damage, facilitator of hemolysis, is not clear yet

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Considering the promising performance of C-KIT inhibitors in MM, now more efforts have been focused on the understanding of the acquired resistance mechanism and the development of new blocking agents to overcome resistance, offering hope for patients with advanced MM and limited treatment options