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Other reported effects include breast tenderness or enlargement in a small percentage of male users, mood changes, and a rare association with high-grade prostate cancer in some analyses (this finding remains debated in the literature)

*Correspondence: Qiao Hong, [email protected] This article was submitted to Gastrointestinal Cancers: Colorectal Cancer, a section of the journal Frontiers in Oncology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Ingesting your vitamins later with food is greatly recommended

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These dosing conventions emerged from practitioner experience and extrapolation from preclinical models