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A dual role for poly-ADP-ribosylation in spatial memory acquisition after traumatic brain injury in mice involving NAD+depletion and ribosylation of 14-3-3gamma

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7.4 Therapeutic potential of microglial regeneration Furthermore, microglial regeneration as a therapeutic approach holds significant promise, with adult brain-resident nestin-positive progenitor cells capable of rapidly proliferating and differentiating into ramified microglia under CSF1R signaling

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It is generally well-tolerated even at higher doses

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2 NPs is overcome by the development of coating technology

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