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Description

The complex is further stabilized by a set of apparently hydrogen bonds formed between the backbone amide of V569 of ASXL1 EBM and the side chain carboxyl group of E657 of BRD4 ET and between the backbone amide of L576 of ASXL1 EBM and the backbone carbonyl of D650 of BRD4 ET

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TNF- is an inflammatory cytokine released primarily from macrophages, T-lymphocytes and natural killer (NK) cells in response to pathogens or trauma

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