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Despite being a promising probiotic candidate, A

In COPD patients, cigarette smoke-induced mtROS cause alterations in mitochondrial fission and fusion proteins, increase oxidative stress-related gene expression, and reduce MMP and ATP levels, leading to impaired mitophagy homeostasis and mitochondrial quality control failure (Santiago et al., 2024)

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Use a mixture of phosphate buffer (prepared by dissolving 6.81 g of potassium dihydrogen phosphate in 1000 mL of water and adjusting the pH to 4.7 with sodium hydroxide test solution) and acetonitrile (35:65) as the mobile phase