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this subject also had the highest thyroid volume during the treatment period

In this review, we discuss how the neonatal Fc receptor (FcRn) acts as a regulator of the high levels of not only IgG Abs, but also albumin, by rescuing both these soluble proteins from cellular catabolism, and how a molecular and cellular understanding of this complex biology has spurred an intense interest in the development of FcRn-targeting strategies for the treatment of IgG-driven autoimmune diseases

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Moreover, immune system-based approaches remove senescent cells by an inflammatory response, which could be problematic in the context of AD where neuroinflammation is present