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However, as F2,6BP levels are typically about one to two orders of magnitude lower than FBP levels, the contribution of F2,6BP to the total fructose bisphosphate pool is probably negligible 44,50

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Also, experiment using acupuncture with metformin for obesity-type PCOS patients with infertility showed much more effective results in reducing BMI, improving hyperandrogenism and IR, and increasing the rate of pregnancy and ovulation compared with acupuncture alone and acupuncture placebo + metformin [146]

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Several reports have supported the notion that taurine enhances the activity of anti-oxidant enzymes (superoxide dismutase-SOD, catalase-CAT, glutathione peroxidase-GPx, glutathione reductase-GR) (6870), preserving redox levels and GSH stores (71)