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Description

G.et al (2019)

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doi: 10.1111/j.1365-2982.2009.01305.x 19

( a ) Co-localization of BRCA1 foci and mCherry DSB foci in U2OS-mCherry-LacI-Fok1 cells treated with the IDH1 inhibitor (IDH1i) alone or supplemented with KG, l-carnitine (l-Carn), or O-acetyl-l-carnitine (Ac-Carn) (DMSO and IDH1i, n = 26

The expression and activity of SIRT1 decrease in aging-related diseases such as COPD, and activating SIRT1 has become an important strategy for treating these diseases