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Autophagy can modulate the expression and activity of apoptosis-related proteins, thereby indirectly altering cellular susceptibility to ferroptosis (38)

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Targeted therapies, including TNF- inhibitors and IL-6 receptor antagonists, effectively reduce inflammation and improve outcomes through cytokine blockade (Smolen, 2020)

(57) found that mustard gas exposure triggered ROS overproduction, upregulation of the ferroptosis gene ACSL4 promoted lipid peroxidation, and downregulation of SLC7A11 and GPX4 weakened cellular defense