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Optic neuropathy: In a 57-year-old woman following use of colloidal silver, by ingestion and by direct application to the skin, nasal mucosa and ear canal, for various ailments

However, insufficient B12 intake is more common in older people, women, African Americans, and people of lower socioeconomic status

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Divalproex sodium, a mixture of valproic acid and sodium valproate, may have fewer gastrointestinal side effects