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The systems toxicology approach integrates multi-level biological data to comprehensively understand systemic molecular and functional changes from an omics-based method using computational modeling to extrapolate classical toxicology findings to risk assessment 15,16

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Smokers are at double the risk of losing teeth when compared to non-smokers

Similarly, no difference in baseline cardiac electrical activity was identified between regular users of electronic cigarettes, regular users of combustible tobacco, and non-users [99]