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There are promising reports of natural compounds (e.g., quercetin, nobiletin) and pharmacological modulators of SIRT5 that may selectively influence its activity

All experimental protocols were approved by Ethics Committee for Animal Experimentation of China Pharmaceutical University

surgical resection, TACE, systemic chemotherapy, and conservative management showed overall survival rates of 11.5, 6.0 ,2.4, and 1.6 months, respectively