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Price: 24.30 USD
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Rating: 4.8982 (28 reviews)

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Description

Nature 547 , 453457 (2017)

NPJ Precis

OP is a common clinical disorder mainly characterized by bone mass loss and bone microarchitectural deterioration (97)

Leaky gut microbiota metabolites SCFA may bind to G protein-coupled receptors, affecting host stem cell metabolism and interfering with insulin signaling, thereby affecting the integrity and activity of the mitochondrial electron transport chain, resulting in an unbalance between glycolysis and OXPHOS, ROS accumulation, and mitochondrial dysfunction ultimately leading to stem cell misdifferentiation and proliferation, causing stem cell exhaustion (Cheng et al., 2010