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Inhibiting the glutathione system induces ferroptosis, a non-apoptotic form of cell death driven by lipid peroxidation, with compounds like withaferin A and altretamine showing strong preclinical activity

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(6) Note that low levels of glutathione have been associated with higher risks of hepatitis, type 2 diabetes, Parkinsons disease, and cancer

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Pavlov VA, Wang H, Czura CJ, Friedman SG, Tracey KJ

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Chemoecology 22(3):169178

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