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It was approved in 2010 for the treatment of HIV associated lipodystrophy, a condition characterized by abnormal fat distribution in individuals living with HIV

These included the -opioid (Cvejic and Devi, 1997), metabotropic glutamate (Romano et al., 1996), and 2 adrenergic (Hebert et al., 1996) receptors

IGF-1 induces skeletal muscle hypertrophy through activation of satellite cells and enhanced protein synthesis. Adams, G.R., American Journal of Physiology-Endocrinology and Metabolism 2

It is not uncommon for individuals to experience emotional suffering and depression due to the social and economic challenges that affect their daily lives [72]