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While the needle puncture injury method provides reliable and consistent experimental disc degeneration models, findings from these studies need to be carefully interpreted and considered in a context dependent manner as the animal caudal spine differs in anatomy, mechanical load, and degrees of motion as compared to the human spine

J., & Wu, J

Iron accumulation and lipid peroxidation occur in the SN, where the death of melanized neurons is the most severe degeneration event in PD, and is associated with more rapid PD progression [136]

In the tolerant variety VA13, had a remarkable rise in ascorbate-glutathione content and ascorbate-glutathione redox status, while the sensitive variety VA15 exhibited negligible increment of ascorbate-glutathione content and ascorbate-glutathione redox status

Given the redundancy of antioxidant mechanisms, different cancer types may rely on distinct oxidative stress responses