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Diagnosis is by recognising the typical oral pattern, gastroenterology workup including colonoscopy and biopsy, blood tests (FBC, CRP, faecal calprotectin) and sometimes biopsy of an oral lesion (showing non-caseating granulomas)

The starting dose of Semaglutide is typically low, and it is gradually increased to ensure the medication is well-tolerated and to minimize any potential side effects