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Initiation of urate-lowering treatment is often delayed, and once begun, many patients continue to have serum urate concentrations above recommended levels for urate crystal dissolution

The Piazza Center - BPC-157 Banned by the FDA?: Discusses FDA's nuanced position and reasons for caution

Effects of heat shock and salinity on barley growth and stress-related gene transcription

[PubMed: 17065669] (Among 181 diabetic patients with sensorimotor polyneuropathy in Russia and Israel treated with ALA [600, 12000 and 1800 mg] or placebo daily for 5 weeks, symptoms improved more with all 3 doses of ALA compared to placebo [by 48%-52% vs 32%], while adverse events that were more frequent with higher doses of ALA included nausea, vomiting and vertigo)

Etzel JP et al