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Arch Biochem Biophys (1997) 346:4552

Acta Pharmacol Sin 43 , 13111323 (2022)

SODs can be categorized into four distinct groups based on the metal cofactors found in their active sites: copper-zinc-SOD (Cu,Zn-SOD), iron SOD (Fe-SOD), manganese SOD (Mn-SOD), and nickel SOD [Bafana et al ., 2011]