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A U-box domain at the N-terminus of the deduced protein sequence between amino acids 9 and 79 (25237 bp in cDNA sequence, Fig

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In this study the patients received one protease inhibitor (indinavir or ritonavir) in combination with two nucleoside analogs (lamivudine plus zidovudine or plus stavudine), suggesting that the HAART ameliorates the oxidative alterations related with HIV-1 infection [43]

Nonetheless, these models cannot fully capture the complexity of three-dimensional tissues or systemic physiology, even when cultured in low-nutrient conditions designed to reflect aspects of the tumour microenvironment