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More recent trials have associated oral propionyl-L-carnitine supplementation (2 g/day for several months) with improved walking distance and claudication onset time (66, 67), as well as with higher pain-free walking distance and higher ankle-brachial index (a diagnostic measure of peripheral arterial disease) (68)

The improvement in the frailty status was less compared to L-carnitine group

[DOI] [PMC free article] [PubMed] [Google Scholar] 158.Plaetzer K., Krammer B., Berlanda J., Berr F., Kiesslich T

Meta-analyses show statistically significant but clinically modest reductions in body weight with L-carnitine supplementation, particularly in older adults and those with obesity or metabolic conditions

Key steps involved in the research process are listed below: 1