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Berberine NPs produced by both APSP and EPN methods have shown promising activities against Gram-positive and Gram-negative bacteria, and yeasts, with NPs prepared through the EPN method showing superior results compared to those made with the APSP method and the unprocessed drug

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Activating immune cells with TLR ligands such as LPS activates Nrf2, reducing proinflammatory cytokines release

Rai A, Patwardhan RS, Jayakumar S, Pachpatil P, Das D, Panigrahi GC, et al