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[DOI] [PubMed] [Google Scholar] 7.Flagg EW, Coates RJ, Eley JW, et al

This process activates oncogenes or inhibits tumor suppressor genes, thereby promoting tumor formation and development

Statements Author contributions QA: Writing original draft

12 mg remains the highest-efficacy dose, but it carries a meaningfully worse GI burden and a correspondingly higher dropout risk

A plaques are formed due to the abnormal cleavage of amyloid precursor protein by - and -secretases that leads to the production and aggregation of toxic peptides in brain