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elegans , eat-2 and eat-18 mutant worms, which are defective in motor neurons related to pharyngeal pumping and, therefore, mimic DR during food intake, are well-established models for understanding how DR impacts metabolism [101]

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Targets NNMT to enhance fat metabolism and reduce fat cell growth

d-Carnitine also increased the anaerobic production of lactic acid and d-citramalic acid from pyruvate, but was associated with reductions in the concentrations of five essential amino acids in tilapia (Leu, Val, Met, Trp and Phe) and higher concentrations of His and (+)-threo-2-amino-3,4-dihydroxybutanoic acid