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Loggers were programmed to take temperature readings every 30 min

Godic A, Poljsak B, Adamic M, Dahmane R

Multiple clinical studies confirm that combining conventional Western drugs like renin-angiotensin system (RAS) inhibitors (e.g., irbesartan) with Chinese herbs such as Astragalus membranaceus (Huangqi), Panax notoginseng (Sanqi), and Rheum palmatum (Dahuang) significantly improves renal function markers and reduces proteinuria

Reducing RIPK3 expression or inhibiting its activity significantly reversed the elevation of cleaved caspase-3 and proapoptotic protein Bax, thereby ameliorating AKI

Overall, RIPC is a potential mitochondria-targeted strategy for protecting the heart and kidneys from ischemia-reperfusion injury, and may be more valuable for patients with prolonged ischemia