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In abdominal aorta anastomosis models, the peptide prevents and reverses thrombus formation, suggesting antithrombotic effects mediated through endothelial protection and normalized coagulation cascade activity

In NMuMG cells and human normal bladder HCV29 cells, TGF- can rewire glycosphingolipid composition to promote EMT by reducing intracellular levels of gangliotetraosylceramide or GM2 (Yamanaka et al., 2004)