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Cleavable linkers enable stimulus-responsive drug liberation, whereas non-cleavable linkers necessitate complete proteolytic degradation of the antibody backbone for payload activation [120, 122]

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Moreover, full-length BPC157 or single-site alanine-mutated BPC157 was dissolved in HBS-EP Buffer (Cytiva) at concentrations ranging from 1.89 nM to 31.25 nM through serial 2-fold dilutions

the diagnostic method of the invention comprises determining in a sample from a subject the levels of at least one marker as defined in Table 6

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