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Clinical trials have also demonstrated that therapy with PBA in combination with vitD3 can promote the clearances of M.tb from the respiratory tract, accelerate sputum culture conversion, reduce clinical symptoms, and promote favorable immunomodulation, thus improving treatment outcomes [146]

The aggressiveness of the tumour is shown by its high propensity of organ invasion and metastasis to the brain, lymph nodes, liver, bone, leptomeninges, and also the bone marrow

Sermorelin preserves the body's natural regulatory feedback loops, whereas steroids suppress endogenous hormone production, creating dependency and potential long-term dysfunction

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Statements Author contributions IM provided critical advice during the writing