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Spread supplemented with moderate doses of vitamin E and carotenoids reduces lipid peroxidation in healthy, nonsmoking adults

5.2.3 Summary box Conclusion: Bile acid and tryptophan-related metabolites (along with their synergistic reprogramming with lipid and redox pathways) constitute a priority candidate mechanism module repeatedly pointed to by multiple studies, potentially linking microbial changes to inflammatory pathway reprogramming

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The biochemical processes associated with biomarkers may reflect an adaptation to compensate for a metabolic defect, such as the apparent increase in glycolytic end products when some mitochondrial processes are compromised